我有一组 4 个 DICOM CT 卷，我正在使用 SimpleITK ImageSeriesReader 阅读它们。其中两张图像代表患者手术前后的 CT。其他两个图像是在前 2 个 CT 图像上分割的二元分割掩模。分割是其源 CT 的 ROI。
所有 4 张 CT 图像，具有不同的大小、间距、原点和方向。我已尝试应用此 GitHub gist https://gist.github.com/zivy/79d7ee0490faee1156c1277a78e4a4c4将我的图像大小调整为 512x512x512 和间距 1x1x1。但是，它不会将图像放置在正确的位置。从图片中可以看出，分割的结构始终位于 CT 图像的中心，而不是正确的位置。
这是我的“原始”DICOM 图像及其肿瘤分割（橙色斑点）。
这是在“调整大小”算法并写入磁盘之后（与以前的图像相同，只是肿瘤因不一致而被涂成绿色斑点）：
用于将所有 4 个 DICOM 卷重新采样到相同尺寸的代码：
def resize_resample_images(images):
""" Resize all the images to the same dimensions, spacing and origin.
Usage: newImage = resize_image(source_img_plan, source_img_validation, ROI(ablation/tumor)_mask)
1. translate to same origin
2. largest number of slices and interpolate the others.
3. same resolution 1x1x1 mm3 - resample
4. (physical space)
Slice Thickness (0018,0050)
ImagePositionPatient (0020,0032)
ImageOrientationPatient (0020,0037)
PixelSpacing (0028,0030)
Frame Of Reference UID (0020,0052)
"""
# %% Define tuple to store the images
tuple_resized_imgs = collections.namedtuple('tuple_resized_imgs',
['img_plan',
'img_validation',
'ablation_mask',
'tumor_mask'])
# %% Create Reference image with zero origin, identity direction cosine matrix and isotropic dimension
dimension = images.img_plan.GetDimension() #
reference_direction = np.identity(dimension).flatten()
reference_size = [512] * dimension
reference_origin = np.zeros(dimension)
data = [images.img_plan, images.img_validation, images.ablation_mask, images.tumor_mask]
reference_spacing = np.ones(dimension) # resize to isotropic size
reference_image = sitk.Image(reference_size, images.img_plan.GetPixelIDValue())
reference_image.SetOrigin(reference_origin)
reference_image.SetSpacing(reference_spacing)
reference_image.SetDirection(reference_direction)
reference_center = np.array(
reference_image.TransformContinuousIndexToPhysicalPoint(np.array(reference_image.GetSize()) / 2.0))
#%% Paste the GT segmentation masks before transformation
tumor_mask_paste = (paste_roi_image(images.img_plan, images.tumor_mask))
ablation_mask_paste = (paste_roi_image(images.img_validation, images.ablation_mask))
images.tumor_mask = tumor_mask_paste
images.ablation_mask = ablation_mask_paste
# %% Apply transforms
data_resized = []
for idx,img in enumerate(data):
transform = sitk.AffineTransform(dimension) # use affine transform with 3 dimensions
transform.SetMatrix(img.GetDirection()) # set the cosine direction matrix
# TODO: check translation when computing the segmentations
transform.SetTranslation(np.array(img.GetOrigin()) - reference_origin) # set the translation.
# Modify the transformation to align the centers of the original and reference image instead of their origins.
centering_transform = sitk.TranslationTransform(dimension)
img_center = np.array(img.TransformContinuousIndexToPhysicalPoint(np.array(img.GetSize()) / 2.0))
centering_transform.SetOffset(np.array(transform.GetInverse().TransformPoint(img_center) - reference_center))
centered_transform = sitk.Transform(transform)
centered_transform.AddTransform(centering_transform)
# Using the linear interpolator as these are intensity images, if there is a need to resample a ground truth
# segmentation then the segmentation image should be resampled using the NearestNeighbor interpolator so that
# no new labels are introduced.
if (idx==1 or idx==2): # temporary solution to resample the GT image with NearestNeighbour
resampled_img = sitk.Resample(img, reference_image, centered_transform, sitk.sitkNearestNeighbor, 0.0)
else:
resampled_img = sitk.Resample(img, reference_image, centered_transform, sitk.sitkLinear, 0.0)
# append to list
data_resized.append(resampled_img)
# assuming the order stays the same, reassigng back to tuple
resized_imgs = tuple_resized_imgs(img_plan=data_resized[0],
img_validation=data_resized[1],
ablation_mask=data_resized[2],
tumor_mask=data_resized[3])
用于将 ROI 分段图像“粘贴”为正确大小的代码。可能是多余的。：
def paste_roi_image(image_source, image_roi):
""" Resize ROI binary mask to size, dimension, origin of its source/original img.
Usage: newImage = paste_roi_image(source_img_plan, roi_mask)
"""
newSize = image_source.GetSize()
newOrigin = image_source.GetOrigin()
newSpacing = image_roi.GetSpacing()
newDirection = image_roi.GetDirection()
if image_source.GetSpacing() != image_roi.GetSpacing():
print('the spacing of the source and derived mask differ')
# re-cast the pixel type of the roi mask
pixelID = image_source.GetPixelID()
caster = sitk.CastImageFilter()
caster.SetOutputPixelType(pixelID)
image_roi = caster.Execute(image_roi)
# black 3D image
outputImage = sitk.Image(newSize, image_source.GetPixelIDValue())
outputImage.SetOrigin(newOrigin)
outputImage.SetSpacing(newSpacing)
outputImage.SetDirection(newDirection)
# transform from physical point to index the origin of the ROI image
# img_center = np.array(img.TransformContinuousIndexToPhysicalPoint(np.array(img.GetSize()) / 2.0))
destinationIndex = outputImage.TransformPhysicalPointToIndex(image_roi.GetOrigin())
# paste the roi mask into the re-sized image
pasted_img = sitk.Paste(outputImage, image_roi, image_roi.GetSize(), destinationIndex=destinationIndex)
return pasted_img