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我正在使用 Bioconductor 的 SRAdb 包。不幸的是，在尝试下载 SRAdb 时，我在 sqliteSendQuery 中遇到错误（见下文）。

有人建议安装最新的 sqlite3 版本。但问题仍然存在。

sqlFile <- getSRAdbFile()

--2016-04-27 16:08:52--  http://dl.dropbox.com/u/51653511/SRAmetadb.sqlite.gz
Resolving dl.dropbox.com (dl.dropbox.com)... 108.160.172.6
Connecting to dl.dropbox.com (dl.dropbox.com)|108.160.172.6|:80... connected.
HTTP request sent, awaiting response... 302 FOUND
Location: http://dl.dropboxusercontent.com/u/51653511/SRAmetadb.sqlite.gz [following]
--2016-04-27 16:08:52--  http://dl.dropboxusercontent.com/u/51653511/SRAmetadb.sqlite.gz
Resolving dl.dropboxusercontent.com (dl.dropboxusercontent.com)... 199.47.217.69
Connecting to dl.dropboxusercontent.com (dl.dropboxusercontent.com)|199.47.217.69|:80... connected.
HTTP request sent, awaiting response... 302 Moved
Location: http://10.137.251.101:15871/cgi-bin/blockpage.cgi?ws-session=4060338223 [following]
--2016-04-27 16:08:52--  http://10.137.251.101:15871/cgi-bin/blockpage.cgi?ws-session=4060338223
Connecting to 10.137.251.101:15871... connected.
HTTP request sent, awaiting response... 200 OK
Length: 1513 (1.5K) [text/html]
Saving to: ‘SRAmetadb.sqlite.gz’

     0K .                                                     100%  208M=0s

2016-04-27 16:08:52 (208 MB/s) - ‘SRAmetadb.sqlite.gz’ saved [1513/1513]

Unzipping...

Error in sqliteSendQuery(con, statement, bind.data) : 
  error in statement: file is encrypted or is not a database
Error in sqliteSendQuery(con, statement, bind.data) : 
  error in statement: file is encrypted or is not a database

这是会话信息：

sessionInfo()

R version 3.2.3 (2015-12-10)
Platform: x86_64-redhat-linux-gnu (64-bit)
Running under: Fedora 23 (Workstation Edition)

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C               LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8    LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C             LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] SRAdb_1.28.1   RCurl_1.95-4.8 bitops_1.0-6   graph_1.48.0  RSQLite_1.0.0  DBI_0.3.1     

loaded via a namespace (and not attached):
[1] parallel_3.2.3      tools_3.2.3         GEOquery_2.36.0     Biobase_2.30.0      BiocGenerics_0.16.1
[6] stats4_3.2.3        XML_3.98-1.4
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1 回答 1

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我觉得有什么问题getSRAdbFile()。看起来文件没有正确下载：

0K .                                                     100%  208M=0s

2016-04-27 16:08:52 (208 MB/s) - ‘SRAmetadb.sqlite.gz’ saved [1513/1513]

我通过使用相同的 url ( http://dl.dropbox.com/u/51653511/SRAmetadb.sqlite.gz) 下载文件，使用wget，解压缩gzip，然后像正常一样从内部开始连接，从而使工作正常进行R。

要将所有内容保留在 内R，您可以使用system2or download.filewith R.utils::gunzip。

于 2016-04-28T18:23:11.850 回答