到目前为止我有这个。
import csv
ifile = open('file', 'rb')
reader = csv.reader(ifile,delimiter='\t')
ofile = open('file', 'wb')
writer = csv.writer(ofile, delimiter='\t')
findlist = ['A', 'G', 'C', 'T', 'Y', 'R', 'W', 'S', 'K', 'M', 'X', 'N', '-']
replacelist = ['AA', 'GG', 'CC', 'TT', 'CT', 'AG', 'AT', 'GC', 'TG', 'CA',
'NN', 'NN', '-']
rep = dict(zip(findlist, replacelist))
def findReplace(find, replace):
s = ifile.read()
s = s.replace(find, replace)
ofile.write(s)
for item in findlist:
findReplace(item, rep[item])
ifile.close()
ofile.close()
它所做的是将 A 替换为 AA。但是我想要的是将所有字母替换为replacelist
. 我对 python 很陌生,不能完全弄清楚为什么它不能替换所有东西。
HE670865 399908 N N N N N
HE670865 399910 N N N N N
HE670865 399945 T T N T T
HE670865 399951 R R N A A
HE670865 399957 A A N A A
HE670865 399978 C C C M C
HE670865 399980 C C C C C
HE670865 399982 T T T T K
HE670865 399984 C C C C C
HE670865 399908 N N N N N
HE670865 399910 N N N N N
HE670865 399945 T T N T T
HE670865 399951 R R N AA AA
HE670865 399957 AA AA N AA AA
HE670865 399978 C C C M C
HE670865 399980 C C C C C
HE670865 399982 T T T T K
HE670865 399984 C C C C C