I made a project based on nested tabs. the nested tabs are different instance of the same viemModel and the same UI. when I switch between the tabs he comboboxes present in the tabs chenge thei selection depending on the tab that is loosing focus.
I add both the viewmodels and the view of my test project. thank you in advance for your help
main window
<Window.Resources>
    <DataTemplate DataType="{x:Type local:IntermediateViewModel}">
        <local:IntermediateView />
    </DataTemplate>
    <DataTemplate x:Key="HeaderedTabItemTemplate">
        <Grid>
            <ContentPresenter
                        Content="{Binding Path=Header, UpdateSourceTrigger=PropertyChanged}" 
                        VerticalAlignment="Center" >
            </ContentPresenter>
        </Grid>
    </DataTemplate>
    <Style x:Key="SimpleTabItemStyle" TargetType="TabItem">
        <Setter Property="Foreground" Value="White"/>
        <Setter Property="FontWeight" Value="Bold"/>
        <Setter Property="Template">
            <Setter.Value>
                <ControlTemplate TargetType="{x:Type TabItem}">
                    <Grid>
                        <Border Name="Border" BorderThickness="1" BorderBrush="#555959">
                            <ContentPresenter x:Name="ContentSite" VerticalAlignment="Center" HorizontalAlignment="Center"
                                 ContentSource="Header" Margin="12,2,12,2" RecognizesAccessKey="True" Height ="40" MinWidth ="90"/>
                        </Border>
                    </Grid>
                    <ControlTemplate.Triggers>
                        <Trigger Property="IsSelected" Value="True">
                            <Setter TargetName="Border" Property="Background" Value="#555959" />
                        </Trigger>
                    </ControlTemplate.Triggers>
                </ControlTemplate>
            </Setter.Value>
        </Setter>
    </Style>
    <DataTemplate x:Key="DefaultTabControlTemplate">
        <TabControl IsSynchronizedWithCurrentItem="True" 
                        BorderThickness="0" 
                        ItemsSource="{Binding}" 
                        ItemTemplate="{StaticResource HeaderedTabItemTemplate}"
                        ItemContainerStyle="{StaticResource SimpleTabItemStyle}"
                        SelectionChanged="TabControl_SelectionChanged"
                        />
    </DataTemplate>
    <!---->
</Window.Resources>
<Grid MinHeight="200" MinWidth="300">
    <Grid.RowDefinitions>
        <RowDefinition Height="260*" />
        <RowDefinition Height="51*" />
    </Grid.RowDefinitions>
    <Border >
        <ContentControl 
            Content="{Binding Path=Workspaces}" 
            ContentTemplate="{DynamicResource DefaultTabControlTemplate}"
             />
    </Border>
    <Button Grid.Row="1" Content="Add" Command="{Binding AddCommand}"/>
</Grid>
view model (create a different istance each time)
class MainWindowViewModel : WorkspacesViewModel<IntermediateViewModel>
{
    public MainWindowViewModel()
    {
        this.WorkspacesView.CurrentChanged += new EventHandler(WorkspacesView_CurrentChanged);
    }
    void WorkspacesView_CurrentChanged(object sender, EventArgs e)
    {
    }
    RelayCommand myVar = null;
    public ICommand AddCommand
    {
        get 
        {
            return myVar ?? (myVar = new RelayCommand(param => 
            {
                SetWindow(new IntermediateViewModel("AA" + this.Workspaces.Count) );
            })); 
        }
    }
first level tab
    <UserControl.Resources>
    <DataTemplate DataType="{x:Type local:ClassViewModel}">
        <local:ClassView />
    </DataTemplate>
</UserControl.Resources>
<Border>
    <ContentControl Content="{Binding Path=CurrentWorkspace, Mode=OneWay}" Loaded="ContentControl_Loaded" DataContextChanged="ContentControl_DataContextChanged" IsVisibleChanged="ContentControl_IsVisibleChanged" LayoutUpdated="ContentControl_LayoutUpdated" TargetUpdated="ContentControl_TargetUpdated" Unloaded="ContentControl_Unloaded" />
</Border>
first level viewmodel
class IntermediateViewModel : WorkspacesViewModel { public string Header { get; set; }
    public IntermediateViewModel(string header)
    {
        Header = header;
        SetWindow(new ClassViewModel(header));
    }
}
nested tab
    <UserControl.Resources>
    <CollectionViewSource x:Key="StatusView" Source="{Binding Path=StatusList}"/>
</UserControl.Resources>
<Grid>
    <ComboBox Name="_spl2Status" ItemsSource="{Binding Source={StaticResource StatusView}}"
      SelectedValue="{Binding Path=MyProperty, Mode=TwoWay, UpdateSourceTrigger=PropertyChanged}"
      SelectedValuePath="FL_TYPE"
      DisplayMemberPath="ID_TYPE" Margin="76,12,0,0" Height="40" VerticalAlignment="Top" HorizontalAlignment="Left" Width="146"
               DataContextChanged="_spl2Status_DataContextChanged"
               IsVisibleChanged="_spl2Status_IsVisibleChanged"
               Loaded="_spl2Status_Loaded"
                SelectionChanged="_spl2Status_SelectionChanged"
               >
    </ComboBox>
</Grid>
nested tab view model
public enum myTypes
{ 
    tipo0 = 0,
    tipo1 = 1,
    tipo2 = 2,
}
class ClassViewModel : WorkspaceViewModel
{
    public ClassViewModel(string name)
    {
        Name = name;
    }
    public string Name { get; set; }
    private List<IntEnumType> _statusList = null;
    public List<IntEnumType> StatusList
    {
        get
        {
            if (_statusList == null)
                _statusList = new List<IntEnumType>()
                {
                    new IntEnumType((int)myTypes.tipo0, myTypes.tipo0.ToString()),
                    new IntEnumType((int)myTypes.tipo1, myTypes.tipo1.ToString()),
                    new IntEnumType((int)myTypes.tipo2, myTypes.tipo2.ToString()),
                };
            return _statusList;
        }
    }
    private int myVar = 1;
    public int MyProperty
    {
        get 
        {
            return myVar; 
        }
        set 
        {
            if (myVar != value)
            {
                myVar = value;
                OnPropertyChanged(() => MyProperty);
            }
        }
    }
}
public class TabItemStyleSelector : StyleSelector
{
    public Style MainTabItem { get; set; }
    public Style ChildrenTabItem { get; set; }
    public Style SpecificationTabItem { get; set; }
    public override Style SelectStyle(object item, DependencyObject container)
    {
        //if (item is IHome)
        //    return MainTabItem;
        //else if (item is SpecificationItemViewModel)
        //    return SpecificationTabItem;
        //else
            return ChildrenTabItem;
    }
}