While not an actual answer, this might at least get you partway to a workable solution. We had a similar situation at a previous employer - lots of data sources, different ways of accessing those data sources, different access permissions, military/government/civilian sources, etc. We used Mule, which is built around the Enterprise Service Bus concept, to connect these data sources to our application. My details are a bit sketchy, as I wasn't the actual implementor, just an integrator, but what we did was define a channel in Mule. Then you write a simple integration piece to go between the channel and the data source, and the application and the channel. The integration piece does the work of making the actual query, and formatting the results, so we had a generic SQL integration piece for accessing a database, and for things like web services, we had some base classes that implemented common functionality, so the actual customization of the integration piecess was a lot less work than it sounds like. The application could then query the channel, which would handle accessing the various data sources, transforming them into a normalized bit of XML, and return the results to the application.
This had a lot of advantages for our situation. We could include new data sources for existing queries by simply connecting them to the channel - the application didn't have to know or care what data sources where there, as it only looked at the data from the channel. Since data can be pushed or pulled from the channel, we could have a data source update the application when, for example, it was updated.
It took a while to get it configured and working, but once we got it going, we were pretty successful with it. In our demo setup, we ended up with 4 or 5 applications acting as both producers and consumers of data, and connecting to maybe 10 data sources.