我试图通过在 Matlab 中编写代码来解决微分方程组。我在这个论坛上发帖,希望有人能以某种方式帮助我。我有一个由 10 个耦合微分方程组成的系统。它是一种载体-宿主流行病模型,它捕捉了一种疾病在人群和昆虫种群之间的传播。由于它是一个简单的微分方程系统,因此我将求解器 ( ode45
) 用于非刚性问题类型。
有 10 个微分方程,每个代表 10 个不同的状态变量。有两个函数具有相同的 10 个耦合 ODE 系统。一个被称为NoEffects_derivative_6_15_2012.m
包含 ODE 的原始系统。调用另一个函数,OnlyLethal_derivative_6_15_2012.m
它包含相同的 ODE 系统,从时间开始,提款率增加gamma=32 %days
,提款率随时间呈指数衰减。
我使用ode45
相同的初始条件来解决这两个系统。两个系统的时间向量也是相同的,从t0
到tfinal
。该向量tspan
包含从t0
到的时间值tfinal
,每个增量为 0.25 天,总共有 157 个时间值。
解值存储在矩阵ye0
和yeL
中。这两个矩阵都包含 157 行和 10 列(对于 10 个状态变量值)。当我比较第 10 个状态变量的值时,对于time=tfinal
矩阵中的ye0
,并yeL
通过绘制差异,我发现它在某些时间值内变为负数。(使用命令:)plot(te0,ye0(:,10)-yeL(:,10))
。这不是预期的。t0
对于从until开始的所有时间值tfinal
,状态变量 10 的值应该更大,因为它是从 ODE 系统获得的解决方案,它没有应用增加的提款率。
我被告知我的 matlab 代码中有一个错误。我不确定如何找出那个错误。或者我正在使用的 matlab 中的求解器 ( ode45
) 效率不高,确实会出现这种问题。任何人都可以帮忙。
我也尝试过ode23
,ode113
但遇到了同样的问题。图 (2) 显示了一条曲线,该曲线对于时间值 32 和 34 变为负数,这表明了一个未预期的结果。对于所有时间值,该曲线应始终具有正值。还有其他任何人可以建议的论坛吗?
这是主要的脚本文件:
clear memory; clear all;
global Nc capitalambda muh lambdah del1 del2 p eta alpha1 alpha2 muv lambdav global dims Q t0 tfinal gamma Ct0 b1 b2 Ct0r b3 H C m_tilda betaHV bitesPERlanding IC global tspan Hs Cs betaVH k landingARRAY muARRAY
Nhh=33898857; Nvv=2*Nhh; Nc=21571585; g=354; % number of public health centers in Bihar state %Fix human parameters capitalambda= 1547.02; muh=0.000046142; lambdah= 0.07; del1=0.001331871263014; del2=0.000288658; p=0.24; eta=0.0083; alpha1=0.044; alpha2=0.0217; %Fix vector parameters muv=0.071428; % UNIT:2.13 SANDFLIES DEAD/SAND FLY/MONTH, SOURCE: MUBAYI ET AL., 2010 lambdav=0.05; % UNIT:1.5 TRANSMISSIONS/MONTH, SOURCE: MUBAYI ET AL., 2010
Ct0=0.054;b1=0.0260;b2=0.0610; Ct0r=0.63;b3=0.0130;
dimsH=6; % AS THERE ARE FIVE HUMAN COMPARTMENTS dimsV=3; % AS THERE ARE TWO VECTOR COMPARTMENTS dims=dimsH+dimsV; % THE TOTAL NUMBER OF COMPARTMENTS OR DIFFERENTIAL EQUATIONS
gamma=32; % spraying is done of 1st feb of the year
Q=0.2554; H=7933615; C=5392890;
m_tilda=100000; % assumed value 6.5, later I will have to get it for sand flies or mosquitoes betaHV=66.67/1000000; % estimated value from the short technical report sent by Anuj bitesPERlanding=lambdah/(m_tilda*betaHV); betaVH=lambdav/bitesPERlanding; IC=zeros(dims+1,1); % CREATES A MATRIX WITH DIMS+1 ROWS AND 1 COLUMN WITH ALL ELEMENTS AS ZEROES
t0=1; tfinal=40; for j=t0:1:(tfinal*4-4) tspan(1)= t0; tspan(j+1)= tspan(j)+0.25; end clear j;
% INITIAL CONDITION OF HUMAN COMPARTMENTS q1=0.8; q2=0.02; q3=0.0005; q4=0.0015; IC(1,1) = q1*Nhh; IC(2,1) = q2*Nhh; IC(3,1) = q3*Nhh; IC(4,1) = q4*Nhh; IC(5,1) = (1-q1-q2-q3-q4)*Nhh; IC(6,1) = Nhh; % INTIAL CONDITIONS OF THE VECTOR COMPARTMENTS IC(7,1) = 0.95*Nvv; %80 PERCENT OF TOTAL ARE ASSUMED AS SUSCEPTIBLE VECTORS IC(8,1) = 0.05*Nvv; %20 PRECENT OF TOTAL ARE ASSUMED AS INFECTED VECTORS IC(9,1) = Nvv; IC(10,1)=0;
Hs=2000000; Cs=3000000; k=1; landingARRAY=zeros(tfinal*50,2); muARRAY=zeros(tfinal*50,2);
[te0 ye0]=ode45(@NoEffects_derivative_6_15_2012,tspan,IC); [teL yeL]=ode45(@OnlyLethal_derivative_6_15_2012,tspan,IC);
figure(1) subplot(4,3,1); plot(te0,ye0(:,1),'b-',teL,yeL(:,1),'r-'); xlabel('time'); ylabel('S'); legend('susceptible humans'); subplot(4,3,2); plot(te0,ye0(:,2),'b-',teL,yeL(:,2),'r-'); xlabel('time'); ylabel('I'); legend('Infectious Cases'); subplot(4,3,3); plot(te0,ye0(:,3),'b-',teL,yeL(:,3),'r-'); xlabel('time'); ylabel('G'); legend('Cases in Govt. Clinics'); subplot(4,3,4); plot(te0,ye0(:,4),'b-',teL,yeL(:,4),'r-'); xlabel('time'); ylabel('T'); legend('Cases in Private Clinics'); subplot(4,3,5); plot(te0,ye0(:,5),'b-',teL,yeL(:,5),'r-'); xlabel('time'); ylabel('R'); legend('Recovered Cases');
subplot(4,3,6);plot(te0,ye0(:,6),'b-',teL,yeL(:,6),'r-'); hold on; plot(teL,capitalambda/muh); xlabel('time'); ylabel('Nh'); legend('Nh versus time');hold off;
subplot(4,3,7); plot(te0,ye0(:,7),'b-',teL,yeL(:,7),'r-'); xlabel('time'); ylabel('X'); legend('Susceptible Vectors');
subplot(4,3,8); plot(te0,ye0(:,8),'b-',teL,yeL(:,8),'r-'); xlabel('time'); ylabel('Z'); legend('Infected Vectors');
subplot(4,3,9); plot(te0,ye0(:,9),'b-',teL,yeL(:,9),'r-'); xlabel('time'); ylabel('Nv'); legend('Nv versus time');
subplot(4,3,10);plot(te0,ye0(:,10),'b-',teL,yeL(:,10),'r-'); xlabel('time'); ylabel('FS'); legend('Total number of human infections');
figure(2) plot(te0,ye0(:,10)-yeL(:,10)); xlabel('time'); ylabel('FS(without intervention)-FS(with lethal effect)'); legend('Diff. bet. VL cases with and w/o intervention:ode45');
函数文件:NoEffects_derivative_6_15_2012
function dx = NoEffects_derivative_6_15_2012( t , x )
global Nc capitalambda muh del1 del2 p eta alpha1 alpha2 muv global dims m_tilda betaHV bitesPERlanding betaVH
dx = zeros(dims+1,1); % t % dx
dx(1,1) = capitalambda-(m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/(x(7,1)+x(8,1))-muh*x(1,1);
dx(2,1) = (m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/(x(7,1)+x(8,1))-(del1+eta+muh)*x(2,1);
dx(3,1) = p*eta*x(2,1)-(del2+alpha1+muh)*x(3,1);
dx(4,1) = (1-p)*eta*x(2,1)-(del2+alpha2+muh)*x(4,1);
dx(5,1) = alpha1*x(3,1)+alpha2*x(4,1)-muh*x(5,1);
dx(6,1) = capitalambda -del1*x(2,1)-del2*x(3,1)-del2*x(4,1)-muh*x(6,1);
dx(7,1) = muv*(x(7,1)+x(8,1))-bitesPERlanding*betaVH*x(7,1)*x(2,1)/(x(6,1)+Nc)-muv*x(7,1);
%dx(8,1) = lambdav*x(7,1)*x(2,1)/(x(6,1)+Nc)-muvIOFt(t)*x(8,1);
dx(8,1) = bitesPERlanding*betaVH*x(7,1)*x(2,1)/(x(6,1)+Nc)-muv*x(8,1);
dx(9,1) = (muv-muv)*x(9,1);
dx(10,1) = (m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/x(9,1);
函数文件:OnlyLethal_derivative_6_15_2012
function dx=OnlyLethal_derivative_6_15_2012(t,x)
global Nc capitalambda muh del1 del2 p eta alpha1 alpha2 muv global dims m_tilda betaHV bitesPERlanding betaVH k muARRAY
dx=zeros(dims+1,1);
% the below code saves some values into the second column of the two arrays % t muARRAY(k,1)=t; muARRAY(k,2)=artificialdeathrate1(t); k=k+1;
dx(1,1)= capitalambda-(m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/(x(7,1)+x(8,1))-muh*x(1,1);
dx(2,1)= (m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/(x(7,1)+x(8,1))-(del1+eta+muh)*x(2,1);
dx(3,1)=p*eta*x(2,1)-(del2+alpha1+muh)*x(3,1);
dx(4,1)=(1-p)*eta*x(2,1)-(del2+alpha2+muh)*x(4,1);
dx(5,1)=alpha1*x(3,1)+alpha2*x(4,1)-muh*x(5,1);
dx(6,1)=capitalambda -del1*x(2,1)-del2*( x(3,1)+x(4,1) ) - muh*x(6,1);
dx(7,1)=muv*( x(7,1)+x(8,1) )- bitesPERlanding*betaVH*x(7,1)*x(2,1)/(x(6,1)+Nc) - (artificialdeathrate1(t) + muv)*x(7,1);
dx(8,1)= bitesPERlanding*betaVH*x(7,1)*x(2,1)/(x(6,1)+Nc)-(artificialdeathrate1(t) + muv)*x(8,1);
dx(9,1)= -artificialdeathrate1(t) * x(9,1);
dx(10,1)= (m_tilda)*bitesPERlanding*betaHV*x(1,1)*x(8,1)/x(9,1);
函数文件:artificialdeathrate1
function art1=artificialdeathrate1(t)
global Q Hs H Cs C
art1= Q*Hs*iOFt(t)/H + (1-Q)*Cs*oOFt(t)/C ;
函数文件:iOFt
function i = iOFt(t)
global gamma tfinal Ct0 b1
if t>=gamma && t<=tfinal
i = Ct0*exp(-b1*(t-gamma));
else
i =0;
end
函数文件:oOFt
function o = oOFt(t)
global gamma Ct0 b2 tfinal
if (t>=gamma && t<=tfinal)
o = Ct0*exp(-b2*(t-gamma));
else
o = 0;
end