svg {
max-width: 500px;
}
.st0,
.st1 {
fill: none;
stroke: #8ea5ae;
stroke-width: 50;
stroke-miterlimit: 10;
}
.st1 {
stroke-linecap: round
}
.st2 {
fill: none;
stroke: #758992;
stroke-width: 50;
stroke-miterlimit: 10;
}
<svg viewBox="0 0 1015 855">
<mask id="myMask">
<!-- Pixels under white are rendered -->
<rect x="0" y="0" width="1015" height="855" fill="white" />
<!-- Pixels under black are hidden -->
<rect class="moveme" x="315" y="335" height="150" width="150" transform="rotate(45 395 395)">
<animateTransform attributeName="transform"
attributeType="XML"
type="scale"
keyTimes="0; 0.25999; 0.26; 1"
values="1; 1; 0; 0"
dur="5s"
additive="sum"
repeatCount="indefinite"/>
</rect>
</mask>
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<!-- Group the circles and apply the mask to the group, not the circles -->
<g mask="url(#myMask)">
<circle r="20" fill="blue">
<animateMotion dur="5s" repeatCount="indefinite" path="M718.54,66.06L294.41,490.19c-48.89,48.89-128.09,48.95-176.91,0.13c-48.82-48.82-48.76-128.02,0.13-176.91
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<circle r="20" fill="blue">
<animateMotion dur="5s" repeatCount="indefinite" path="M753.9,101.42c0,0-424.26,424.26-424.26,424.26c-68.34,68.34-179.15,68.34-247.49,0s-68.34-179.15,0-247.49
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</circle>
<circle r="20" fill="blue">
<animateMotion dur="5s" repeatCount="indefinite" path="M683.19,30.7L258.92,454.97c-29.29,29.29-76.78,29.29-106.07,0c-29.29-29.29-29.29-76.78,0-106.07
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</circle>
</g>
<!-- uncomment the rect below to visualize the animation applied to the mask -->
<!-- <rect x="315" y="335" height="150" width="150" fill="#f00" opacity=".1" transform="rotate(45 395 395)">
<animateTransform attributeName="transform"
attributeType="XML"
type="scale"
keyTimes="0; 0.25999; 0.26; 1"
values="1; 1; 0; 0"
dur="5s"
additive="sum"
repeatCount="indefinite"/>
</rect>-->
</svg>