I'm writing a WinForms C# application on a 4K laptop in Visual Studio Community 2017. By default I have my Windows 10 Pro scaled to 150%. I have AutoScaleMode = none on every form and every user control.
I run my application and yet it still is scaled to 150%. I'm running VS as a DPI unaware process, and at design time my control are the right (small) size. I don't think it matters but I thought I'd mention it anyway.
Running Windows 10 Pro, fully updated.