Considering the accepted answer and its comments, I would reconsider Jester's advice (which seems to me only +4B when compared to proposed Z80 code, but with somewhat different code layout, i.e. where less/greater_equal branches reside, which may further complicate or simplify your code ... plus it should perform better than doing xor 0x80 every time to both D and H):
mov a,d
xra h
jp sameSigns ; as "JNS" in 8086 / "jp p," in Z80
; sign bits are different, signed overflow may happen
; but if H positive, then DE is less than HL
xra d ; make A=H and set sign flag
jm DeIsGreaterEqualThanHl
:DeIsLessThanHl
; DE < HL
...
:sameSigns
; sign bits are equal, it is safe to do ordinary sub
mov a,e
sub l
mov a,d
sbb h
jc DeIsLessThanHl
:DeIsGreaterEqualThanHl
; DE >= HL
...
You can also modify it as procedure which returns CF=1 when DE<HL by doing:
:SignedCmpDeHl
mov a,d
xra h
jp sameSigns ; as "JNS" in 8086 / "jp p," in Z80
; sign bits are different, signed overflow may happen
; but if H positive, then DE is less than HL
xra d ; make A=H and set sign flag (CF=0)
rm ; return CF=0 when DE >= HL (H is negative)
stc
ret ; return CF=1 when DE < HL (H is positive/zero)
:sameSigns
; sign bits are equal, it is safe to do ordinary sub
mov a,e
sub l
mov a,d
sbb h
ret ; return with CF=1 when DE < HL (CF=0 DE >= HL)
BTW you can turn CF=0/1 into A=0/~0 by sbb a
- sometimes that 0/255
is handy for further calculations...
But as I commented under question, many time this is worth of revisit on architectural level, to see if the whole code logic can't be turned into unsigned 0..FFFF mode of operation, maybe it would lead to adjusting (by -32768) values like "_left" just at one/two specific spots (like final output to user), while many more other internal comparisons/usages would work in unsigned way.
EDIT:
Some variants for compares against constants (for one-time constant it's probably better (size-wise) to just load it into other RP and use the generic RP1 vs RP2 compare, especially if you have spare RP and the generic compare is already instantiated for other code ... but for multiple uses of the same constant this will probably win both size-wise and speed-wise ... inlining wins speed-wise? May get on par with subroutine, depends how the result is used).
reg-pair (actually also any 8b reg) against zero:
; signed compare 8b or 16b register vs 0, into SF, destroys A
xra a ; A=0
ora R ; 16b R=[HDB], or any 8b R: SF = (RP < 0 or R < 0)
...i.e. "jm hlIsLessThanZero"
; signed compare 8b or 16b register vs 0, into CF, destroys A
mov a,R ; 16b R=[HDB], or any 8b R
ral ; CF = (RP < 0) or (R < 0)
...i.e. "jc hlIsLessThanZero" or "sbb a" to get 0/255
reg-pair against any 16b #XY constant:
; signed 16b compare RP (HL/DE/BC) vs nonzero constant #XY
; subroutine, returns CF=1 if RP < #XY, modifies A
mov a,R
xri 0x80 ; convert 8000..7FFF into 0000..FFFF
cpi #X^0x80 ; "X" is xor-ed with 0x80 too to have it in 0000..FFFF range
rnz ; if ZF=0, then CF=1 is (RP < XY) and CF=0 is (RP > XY)
; R == X, the low 8b P vs Y will decide
mov a,P
cpi #Y ; CF=1 if (RP < XY)
ret ; 10B for particular #XY constant and RP
; inlined form
mov a,R
xri 0x80 ; convert 8000..7FFF into 0000..FFFF
cpi #X^0x80 ; "X" is xor-ed with 0x80 too to have it in 0000..FFFF range
jnz HiByteWasDecisive ; if ZF=0, then CF is set correctly, done
mov a,P ; R == #X, the low 8b P vs #Y will decide final CF
cpi #Y ; CF=1 if (RP < #XY)
:HiByteWasDecisive
; CF=1 is (RP < #XY) and CF=0 is (RP >= #XY)
...