You can start with a special "table" (or file in Unidata terminology) named VOC - it will have a list of all the other files that are in your current "database" (aka account), as well as a bunch of other things.
To get a list of files in (or pointed to) the current account:
:SORT VOC WITH F1 = "F]" "L]" "DIR" F1 F2
Try HELP CREATE.FILE
if you're curious about the difference between F and LF and DIR.
Once you have a list of files, weed out the ones named *TEMP*
or *WORK*
and start digging into the ones that seem important. There are other ways to get at what's important (e.g using triggers or timestamps), but browsing isn't a bad idea to see what conventions are used.
Once you have a file that looks interesting (let's say CUSTOMERS), you can look at the dictionary of that file to see
:SORT DICT CUSTOMERS F1 F2 BY F1 BY F2 USING DICT VOC
It can help to create something like F2.LONG in DICT VOC to increase the display size up from 15 characters.
Now you have a list of "columns" (aka fields or attributes), you're looking for D-type attributes that will tell you what columns are in the file. V or I-type's are calculations
https://github.com/ianmcgowan/SCI.BP/blob/master/PIVOT is helpful with profiling when you see an attribute that looks interesting and you want to see what the data looks like.
http://docs.rocketsoftware.com/nxt/gateway.dll/RKBnew20/unidata/previous%20versions/v8.1.0/unidata_userguide_v810.pdf has some generally good information on the concepts and there are many other online manuals available there. It can take a lot of reading to get to the right thing if you don't know the terminology.