我见过很多人遇到同样的问题，但我还没有找到解决方案。我已经向 GATKs CombineVariants 提供了 24 个 VCF4.1 文件 ( http://evs.gs.washington.edu/EVS/ )。我收到此错误：
##### ERROR MESSAGE: Invalid command line: No tribble type was provided on the command line and the type of the file could not be determined dynamically. Please add an explicit type tag :NAME listing the correct type from among the supported types:
##### ERROR Name FeatureType Documentation
##### ERROR BCF2 VariantContext (this is an external codec and is not documented within GATK)
##### ERROR VCF VariantContext (this is an external codec and is not documented within GATK)
##### ERROR VCF3 VariantContext (this is an external codec and is not documented within GATK)
我曾在 GATKs 支持处询问过，但没有好的答案。我使用 VCFtools 进行验证，它们都通过了，但有两个非严重警告：
The header tag 'reference' not present. (Not required but highly recommended.)
The header tag 'contig' not present for CHROM=chr10. (Not required but highly recommended.)
有谁知道？