不幸的是，您需要手动触发该change事件。并且使用事件构造器将是最好的解决方案。

var select = document.querySelector('#sel'),
    input = document.querySelector('input[type="button"]');
select.addEventListener('change',function(){
    alert('changed');
});
input.addEventListener('click',function(){
    select.value = 2;
    select.dispatchEvent(new Event('change'));
});

<select id="sel" onchange='alert("changed")'>
  <option value='1'>One</option>
  <option value='2'>Two</option>
  <option value='3' selected>Three</option>
</select>
<input type="button" value="Change option to 2" />

当然，EventIE 也不支持构造函数。所以你可能需要用这个来填充：

function Event( event, params ) {
    params = params || { bubbles: false, cancelable: false, detail: undefined };
    var evt = document.createEvent( 'CustomEvent' );
    evt.initCustomEvent( event, params.bubbles, params.cancelable, params.detail );
    return evt;
}

我的解决方案的小提琴就在这里。但以防万一它过期，我也会粘贴代码。

HTML：

<select id="sel">
  <option value='1'>One</option>
  <option value='2'>Two</option>
  <option value='3'>Three</option>
</select>
<input type="button" id="button" value="Change option to 2" />

JS：

var sel = document.getElementById('sel'),
    button = document.getElementById('button');

button.addEventListener('click', function (e) {
    sel.options[1].selected = true;

    // firing the event properly according to StackOverflow
    // http://stackoverflow.com/questions/2856513/how-can-i-trigger-an-onchange-event-manually
    if ("createEvent" in document) {
        var evt = document.createEvent("HTMLEvents");
        evt.initEvent("change", false, true);
        sel.dispatchEvent(evt);
    }
    else {
        sel.fireEvent("onchange");
    }
});

sel.addEventListener('change', function (e) {
    alert('changed');
});

就这么简单：

var sel = document.getElementById('sel');
var button = document.getElementById('button');

button.addEventListener('click', function (e) {
    sel.options[1].selected = true;
    sel.onchange();
});

但是这种方式有问题。您不能像使用普通函数那样调用事件，因为可能有多个函数在侦听一个事件，并且可以通过几种不同的方式设置它们。

不幸的是，触发事件的“正确方法”并不那么容易，因为您必须在 Internet Explorer（使用 document.createEventObject）和 Firefox（使用 document.createEvent("HTMLEvents")）中以不同的方式进行操作

var sel = document.getElementById('sel');
var button = document.getElementById('button');

button.addEventListener('click', function (e) {
    sel.options[1].selected = true;
    fireEvent(sel,'change');

});


function fireEvent(element,event){
    if (document.createEventObject){
    // dispatch for IE
    var evt = document.createEventObject();
    return element.fireEvent('on'+event,evt)
    }
    else{
    // dispatch for firefox + others
    var evt = document.createEvent("HTMLEvents");
    evt.initEvent(event, true, true ); // event type,bubbling,cancelable
    return !element.dispatchEvent(evt);
    }
}

整个创建和调度事件都有效，但由于您使用的是onchange属性，您的生活可以更简单一些：

http://jsfiddle.net/xwywvd1a/3/

var selEl = document.getElementById("sel");
selEl.options[1].selected = true;
selEl.onchange();

如果您使用浏览器的事件 API（addEventListener、IE 的 AttachEvent 等），那么您将需要创建和调度事件，正如其他人已经指出的那样。

尝试这个：

<select id="sel">
 <option value='1'>One</option>
  <option value='2'>Two</option> 
  <option value='3'>Three</option> 
  </select> 


  <input type="button" value="Change option to 2"  onclick="changeOpt()"/>

  <script>

  function changeOpt(){
  document.getElementById("sel").options[1].selected = true;

alert("changed")
  }

  </script>

These questions may be relevant to what you're asking for:

• How can I trigger an onchange event manually?

• How to trigger an event in an input field changed with javascript

Here are my thoughts: You can stack up more than one call in your onclick event like this:

<select id="sel" onchange='alert("changed")'>
  <option value='1'>One</option>
  <option value='2'>Two</option>
  <option value='3'>Three</option>
</select>
<input type="button" onclick='document.getElementById("sel").options[1].selected = true; alert("changed");' value="Change option to 2" />

You could also call a function to do this.

If you really want to call one function and have both behave the same way, I think something like this should work. It doesn't really follow the best practice of "Functions should do one thing and do it well", but it does allow you to call one function to handle both ways of changing the dropdown. Basically I pass (value) on the onchange event and (null, index of option) on the onclick event.

Here is the codepen: http://codepen.io/mmaynar1/pen/ZYJaaj

<select id="sel" onchange='doThisOnChange(this.value)'>
<option value='1'>One</option>
<option value='2'>Two</option>
<option value='3'>Three</option>
</select>
<input type="button" onclick='doThisOnChange(null,1);' value="Change option to 2"/>

<script>
doThisOnChange = function( value, optionIndex)
{
    if ( optionIndex != null )
    {
       var option = document.getElementById( "sel" ).options[optionIndex];
       option.selected = true;
       value = option.value;
    }
    alert( "Do something with the value: " + value );
}
</script>

使用 Razor 的 html:

 @Html.DropDownList("test1", Model.SelectOptionList, new { id = "test1", onchange = "myFunction()" })

JS代码：

function myFunction() {

            var value = document.getElementById('test1').value;

            console.log("it has been changed! to " + value );
        }

您可以在更改 onclick 事件的选定选项后手动触发事件：document.getElementById("sel").onchange();