这是我第一次使用 read.table 遇到这个问题:对于具有大量列的行条目,read.table 将列条目循环到下一行。
我有一个 .txt 文件,其中包含可变长度且长度不等的行。作为参考,这是我正在阅读的 .txt 文件:http ://www.broadinstitute.org/gsea/msigdb/download_file.jsp?filePath=/resources/msigdb/4.0/c5.bp.v4.0.symbols.gmt
这是我的代码:
tabsep <- gsub("\\\\t", "\t", "\\t")
MSigDB.collection = read.table(fileName, header = FALSE, fill = TRUE, as.is = TRUE, sep = tabsep)
部分输出:第一列
V1 V2 V3 V4 V5 V6
1 TRNA_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/TRNA_PROCESSING ADAT1 TRNT1 FARS2
2 REGULATION_OF_BIOLOGICAL_QUALITY http://www.broadinstitute.org/gsea/msigdb/cards/REGULATION_OF_BIOLOGICAL_QUALITY DLC1 ALS2 SLC9A7
3 DNA_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/DNA_METABOLIC_PROCESS XRCC5 XRCC4 RAD51C
4 AMINO_SUGAR_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/AMINO_SUGAR_METABOLIC_PROCESS UAP1 CHIA GNPDA1
5 BIOPOLYMER_CATABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/BIOPOLYMER_CATABOLIC_PROCESS BTRC HNRNPD USE1
6 RNA_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/RNA_METABOLIC_PROCESS HNRNPF HNRNPD SYNCRIP
7 INTS6 LSM5 LSM4 LSM3 LSM1
8 CRK
9 GLUCAN_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/GLUCAN_METABOLIC_PROCESS GCK PYGM GSK3B
10 PROTEIN_POLYUBIQUITINATION http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_POLYUBIQUITINATION ERCC8 HUWE1 DZIP3
...
部分输出:最后一列
V403 V404 V405 V406 V407 V408 V409 V410 V411 V412 V413 V414 V415 V416 V417 V418 V419 V420 V421
1
2 CALCA CALCB FAM107A CDK11A RASGRP4 CDK11B SYN3 GP1BA TNN ENO1 PTPRC MTL5 ISOC2 RHAG VWF GPI HPX SLC5A7 F2R
3
4
5
6 IRF2 IRF3 SLC2A4RG LSM6 XRCC6 INTS1 HOXD13 RP9 INTS2 ZNF638 INTS3 ZNF254 CITED1 CITED2 INTS9 INTS8 INTS5 INTS4 INTS7
7 POU1F1 TCF7L2 TNFRSF1A NPAS2 HAND1 HAND2 NUDT21 APEX1 ENO1 ERF DTX1 SOX30 CBY1 DIS3 SP1 SP2 SP3 SP4 NFIC
8
9
10
例如,第 6 行的列条目被循环填充以填充第 7 行和第 8 行。对于具有大量列的行条目,我似乎只有这个问题。其他 .txt 文件也会出现这种情况,但会在不同的列号处中断。我检查了发生中断的所有行条目,并且条目中没有异常字符(它们都是标准的大写基因符号)。
我已经尝试了 read.table 和 read.delim ,结果相同。如果我先将 .txt 文件转换为 .csv 并使用相同的代码,则不会出现此问题(请参阅下面的等效输出)。但我不想先将每个文件转换为 .csv,我真的只想了解发生了什么。
如果我转换为 .csv 文件,则输出正确:
MSigDB.collection = read.table(fileName, header = FALSE, fill = TRUE, as.is = TRUE, sep = ",")
V1 V2 V3 V4 V5 V6
1 TRNA_PROCESSING http://www.broadinstitute.org/gsea/msigdb/cards/TRNA_PROCESSING ADAT1 TRNT1 FARS2 METTL1
2 REGULATION_OF_BIOLOGICAL_QUALITY http://www.broadinstitute.org/gsea/msigdb/cards/REGULATION_OF_BIOLOGICAL_QUALITY DLC1 ALS2 SLC9A7 PTGS2
3 DNA_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/DNA_METABOLIC_PROCESS XRCC5 XRCC4 RAD51C XRCC3
4 AMINO_SUGAR_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/AMINO_SUGAR_METABOLIC_PROCESS UAP1 CHIA GNPDA1 GNE
5 BIOPOLYMER_CATABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/BIOPOLYMER_CATABOLIC_PROCESS BTRC HNRNPD USE1 RNASEH1
6 RNA_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/RNA_METABOLIC_PROCESS HNRNPF HNRNPD SYNCRIP MED24
7 GLUCAN_METABOLIC_PROCESS http://www.broadinstitute.org/gsea/msigdb/cards/GLUCAN_METABOLIC_PROCESS GCK PYGM GSK3B EPM2A
8 PROTEIN_POLYUBIQUITINATION http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_POLYUBIQUITINATION ERCC8 HUWE1 DZIP3 DDB2
9 PROTEIN_OLIGOMERIZATION http://www.broadinstitute.org/gsea/msigdb/cards/PROTEIN_OLIGOMERIZATION SYT1 AASS TP63 HPRT1