这将基本上创建你想要的.. 可能需要一些小的修改..
import wx
a = wx.App(redirect=False)
f = wx.Frame(None,-1,"application")
p = wx.Panel(f,-1)
sb = wx.StaticBox(p,-1,"label")
sb_sz = wx.StaticBoxSizer(sb,wx.VERTICAL)
sb_sz.Add(wx.CheckBox(p,-1,"CB 1",size=(200,-1)),0,wx.ALL,10)
sb_sz.Add(wx.CheckBox(p,-1,"CB 2"),0,wx.ALL,10)
sb_sz.AddSpacer(7)
sz_h = wx.BoxSizer(wx.HORIZONTAL)
sz_h.Add(wx.StaticText(p,-1,"Some Label"),0,wx.ALL,10)
sz_h.Add(wx.Choice(p,-1,choices = ["A","B","C"]))
sb_sz.Add(sz_h)
sb_sz.AddSpacer(35)
sz = wx.BoxSizer(wx.VERTICAL)
sz.Add(sb_sz,0,wx.ALL,10)
p.SetSizer(sz)
sz_h2 = wx.BoxSizer(wx.HORIZONTAL)
sz_h2.Add(wx.Button(p,wx.ID_OK))
sz_h2.Add(wx.Button(p,wx.ID_CANCEL))
sz.Add(sz_h2,0,wx.ALIGN_RIGHT|wx.ALL,10)
sz2 = wx.BoxSizer()
f.SetSizer(sz2)
sz2.Add(p)
f.Layout()
f.Fit()
f.Show()
a.MainLoop()