It's not recommended to mess with the internals of backbone inheritance and use the provided methods and flow to achieve model manipulation on initialization. To do that - in a similar fashion as with collections, views or routers you have an initialization method that you should override that takes the role of a constructor.
If you need to alter all your models just create a new base class that you will later use as a super class for all your models and then if you need to overwrite the initialization method of subclasses remeber to call the super class initializer using the built in backbone class __super__
property.
initialize: function() {
this.constructor.__super__.initialize.call(this);
// whatever
},
Altering the core of backbone will never do good for you in the long run as it my prevent you from being able to easily update to new version if they would introduce conflicting changes.
I've been there and done that - and after doing it I'd recommend not following this path to anybody!