Good idea, don't post good idea's online ;-)
I'm going to tell you up front; unless you are lucky I don't think you will be able to get this to work.
I know that someone once found out that iTunes uses some kind of daemon program to communicate with your iDevices. I'm not sure if this is still true, but that daemon is undocumented but 'available'. I have no more clues than this, maybe you get lucky and find something on Google.
I'd go with wireless communication, I don't think speed is such an issue if we're talking about small instruction sets.
Also there's this, but I'm not sure if that will be of any help to you.
UPDATE:
found this post: Where is the mount point for the iPod/iPhone in Mac?
Which should help you write to the iDevice disk. You should be able to continuously look for filesystem updates on your device to process the data, and vice versa, to establish some kind of transfer system.