最基本的多域场景是
static void Main()
{
    AppDomain newDomain = AppDomain.CreateDomain("New Domain");
    newDomain.ExecuteAssembly("file.exe");
    AppDomain.Unload(newDomain);
}
调用ExecuteAssembly单独的域很方便,但不提供与域本身交互的能力。它还要求目标程序集是可执行文件,并强制调用者进入单个入口点。为了结合一些灵活性,您还可以将字符串或参数传递给 .exe。
我希望这有帮助。
扩展:然后尝试以下操作
AppDomainSetup setup = new AppDomainSetup();
setup.AppDomainInitializer = new AppDomainInitializer(ConfigureAppDomain);
setup.AppDomainInitializerArguments = new string[] { unknownAppPath };
AppDomain testDomain = AppDomain.CreateDomain("test", AppDomain.CurrentDomain.Evidence, setup);
AppDomain.Unload(testDomain);
File.Delete(unknownAppPath);
可以AppDomain按如下方式初始化
public static void ConfigureAppDomain(string[] args)
{
    string unknownAppPath = args[0];
    AppDomain.CurrentDomain.DoCallBack(delegate()
    {
        //check that the new assembly is signed with the same public key
        Assembly unknownAsm = AppDomain.CurrentDomain.Load(AssemblyName.GetAssemblyName(unknownAppPath));
        //get the new assembly public key
        byte[] unknownKeyBytes = unknownAsm.GetName().GetPublicKey();
        string unknownKeyStr = BitConverter.ToString(unknownKeyBytes);
        //get the current public key
        Assembly asm = Assembly.GetExecutingAssembly();
        AssemblyName aname = asm.GetName();
        byte[] pubKey = aname.GetPublicKey();
        string hexKeyStr = BitConverter.ToString(pubKey);
        if (hexKeyStr == unknownKeyStr)
        {
            //keys match so execute a method
            Type classType = unknownAsm.GetType("namespace.classname");
            classType.InvokeMember("MethodNameToInvoke", BindingFlags.InvokeMethod, null, null, null);
        }
    });
}